1818 Church organized by Rev. Jeremiah Chaplin, first president of Colby College in the farmhouse on the site later occupied by the Elmwood Hotel. Chaplin was the first pastor of this church as well as president of the college.
1820 Baptism of George Dana Boardman, first graduate of the college and this church's first foreign missionary .
1824 Organization of the First Baptist Society, a legal entity to hold property. The Society sold pews to finance the meetinghouse.
1826 Meetinghouse completed at a cost of less than $4,000 and fittingly dedicated. The main part of the building still rests on the original foundation.
1831 Church sponsored a new church at Ten Lots.
1834 Samuel Francis Smith, author of 'America', called to the pastorate.
1835 Beginning of work with the French Canadians that led to eventual formation of Second Baptist Church.
1836- 1904 Additions to the building, made at four separate times, culminating in the present vestries, classrooms, parlors, and dining facilities.
1844 Hanging of the church bell.
1855 First major alterations to the sanctuary saw removal of doors from pews, lowering of the high pulpit, and carpeting the floor.
1866 Acceptance into membership of Samuel Osborne, former Negro slave, on his own statement that he had been baptised and accepted into a church in Culpepper, Virginia, where the Civil War had destroyed all records.
1874 Vote to free the pews.
1875 Complete remodelling of the building, including new, modern pews. Services meanwhile were held in the Unitarian Church.
1879 Two consecutive pastorates that encompassed thirty-five years: William Spencer, 1879-1899; Edwin Whittemore 1899-1914.
1889 Installation of electric lighting.
1901 Incorporation of First Baptist Church of Waterville under new law permitting churches to hold property. This ended the distinction between 'Church' and 'Society'.
1903 College Librarian Edward W. Hall completed thirty years as church clerk.